20 Facts You Should Know About Immunotherapy Treatment

FACT #17:Focused ultrasound is being used to disrupt tumor defenses.

Focused ultrasound technology, commonly known for its use in pregnancy monitoring, is being harnessed to battle cancer. While high-intensity ultrasound waves can directly destroy tumors, their real potential lies in supporting the immune system's actions.

Tumors can thwart immune responses not only through checkpoint pathways but also by physical barriers that block immune cells and immunotherapy drugs. For example, the blood-brain barrier shields brain tumors from treatment. Additionally, "leaky" blood vessels can hinder drug delivery to tumors in various locations.

To overcome these challenges, scientists are using an image-guided approach with focused ultrasound. This technique manipulates microbubbles to disrupt these defenses.