20 Facts You Should Know About Immunotherapy Treatment

FACT #15:Immunotherapy treatment isn't just for humans; it works for dogs too!

Cancer is a common issue in older dogs, and the University of Pennsylvania is at the forefront of extending immunotherapy's benefits to our furry friends. The Penn Vet Cancer Center and the Mason Canine Cancer Immunotherapy Research are leading these efforts.

Dr. Mason's team has treated many dogs. For example, Lewis, a golden retriever with bone cancer: After a limb-sparing procedure, Lewis received a genetically modified bacteria similar to CRS-207, targeting a tumor-specific protein. This bacterial vaccine aims to activate his immune system against hidden metastases and provide long-term protection if cancer returns.

But vaccines are just one approach. Kobe is having his immune system engineered to produce tumor-targeting antibodies, while Harley has undergone anti-CD20 CAR T cell immunotherapy for leukemia. These treatments offer hope to dogs battling cancer.